⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616634 | 0.87 | — | — | |
| SCHEMBL11616632 | 0.87 | — | — | |
| SCHEMBL11064009 | 0.83 | — | — | |
| SCHEMBL11064608 | 0.83 | — | — | |
| SCHEMBL3870701 | 0.80 | APEX1 (0.33) | — | |
| SCHEMBL10708826 | 0.78 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL701380 | 0.75 | ALDH1A1 (0.32) | — | |
| Bromide SCHEMBL11228885 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL11161524 | 0.73 | — | — | |
| SCHEMBL3062687 | 0.71 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52057163-A | — | — | None | — | — | JP | disclosed |
| JP-52100463-A | — | — | None | — | — | JP | disclosed |
| JP-52083734-A | — | — | None | — | — | JP | disclosed |
| US-4468521-A | Method of producing gamma-halogeno-delta unsaturated carboxylic acid esters | KURARAY CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4458090-A | RECYCLING LACTONE BY-PRODUCT | KURARAY CO., LTD. (JP) | 1984-07-03 | — | — | US | disclosed |
| US-4409238-A | Insecticides and insecticidal compositions | KURARAY CO., LTD. (JP) | 1983-10-11 | — | — | US | disclosed |
| EP-0025931-B1 | PROCESS FOR THE PREPARATION OF 5-(2,2-DIHALOGENVINYL)-4,4-DIALKYL-TETRAHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1983-03-09 | — | — | EP | disclosed |
| EP-0025935-B1 | PROCESS FOR THE PREPARATION OF 5-(2,2,2,-TRIHALOGEN-ETHYL)-DIALKYL-TETRAHYDROFURAN-2-ONES | BASF Aktiengesellschaft (DE) | 1982-12-22 | — | — | EP | disclosed |
| US-4324725-A | Preparation of 5-(2,2-dihalovinyl)-4,4-dialkyl-tetrahydro-furan-2-ones | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |
| US-4310464-A | Lactones | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-01-12 | — | — | US | disclosed |
| EP-0025935-A1 | Process for the preparation of 5-(2,2,2,-trihalogen-ethyl)-dialkyl-tetrahydrofuran-2-ones | BASF Aktiengesellschaft (DE) | 1981-04-01 | — | — | EP | disclosed |
| US-4225704-A | Preparation of halogenovinyl-substituted tetra-hydrofuran-2-ones | BAYER AKTIENGESELLSCHAFT (DE) | 1980-09-30 | — | — | US | disclosed |
| US-4195033-A | 1-Acetyl or 1-cyano-2(2,2-dichlorovinyl)-3,3-dimethyl cyclopropane | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-03-25 | — | — | US | disclosed |
| EP-0005472-A2 | Process for the preparation of substituted gamma-halogen carboxylic acid esters | BAYER AG (DE) | 1979-11-28 | — | — | EP | disclosed |
| EP-0001089-A1 | Process for the preparation of halogenovinyl-substituted 2-tetrahydrofuranones, selected halogenovinyl-substituted 2-tetrahydrofuranones | BAYER AG (DE) | 1979-03-21 | — | — | EP | disclosed |
| US-4102896-A | Preparation of a 5-(2,2-dihalovinyl)-4,4-dimethyl-2-oxotetrahydrofuran | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-07-25 | — | — | US | disclosed |
| US-4083855-A | Method for producing a γ-lactone | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-11 | — | — | US | disclosed |
| JP-S52100463-A | GAMMA-LACTONE AND METHOD OF PREPARING SAME | SUMITOMO CHEM CO LTD | 1977-08-23 | — | — | JP | disclosed |
| JP-S5283734-A | GAMMA-LACTONE DERIVATIVES AND PREPARATION THEREOF | KURARAY CO LTD | 1977-07-12 | — | — | JP | disclosed |
| JP-S5257163-A | PROCESS FOR PREPARING GAMMA-LACTONES | KURARAY CO LTD | 1977-05-11 | — | — | JP | disclosed |