Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10982608 | 0.85 | MAPT (0.54) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL10708221 | 0.85 | NPC1 (0.56) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL20716378 | 0.84 | NPC1 (0.74) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL11055339 | 0.83 | NPC1 (0.52) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL30689191 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL1665694 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL4093686 | 0.82 | SMN1; SMN2 (0.61) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL2744730 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL20703336 | 0.82 | NPC1 (0.50) | SMN1; SMN2KMT2AMAPTMEN1LMNA | |
| SCHEMBL20716309 | 0.81 | NPC1 (0.52) | SMN1; SMN2MAPTLMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0082109-A2 | Substituted 2-hydroxyphenylacetic acids and derivatives of them | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |