SCHEMBL11062673

SCHEMBL11062673

CC(C)(C)C1=CC(O)(c2occc2Cl)C=C(C(C)(C)C)C1=O

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11062446 0.72 POLB (0.57) POLBGPR55
SCHEMBL11429428 0.65 POLB (0.70) POLBGPR55
SCHEMBL10705080 0.65 POLB (0.59) POLBGPR55
SCHEMBL7213737 0.65 POLB (0.55) POLBGPR55
SCHEMBL13886742 0.64 POLB (0.53) POLBGPR55
SCHEMBL10990177 0.64 POLB (0.50) POLBGPR55
SCHEMBL11426233 0.64 GPR55 (0.63) POLBGPR55
SCHEMBL11492393 0.62 POLB (0.57) POLBGPR55
SCHEMBL11036021 0.62 POLB (0.57) POLBGPR55
SCHEMBL11425808 0.61 POLB (0.58) POLBGPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4431831-A ANTIINFLAMMATORY AND ANTIARTHRITIC AGENTS RIKER LABORATORIES, INC. (US) 1984-02-14 US disclosed
EP-0080356-A2 Substituted furans RIKER LABORATORIES, INC. (US) 1983-06-01 EP disclosed
US-4357345-A ANTIINFLAMMATORY AGENTS RIKER LABORATORIES, INC. (US) 1982-11-02 US disclosed