Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213737 | 0.69 | POLB (0.55) | POLBGPR55ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9861297 | 0.68 | POLB (0.50) | POLBGPR55ALDH1A1MAPTMCL1 | |
| SCHEMBL13886742 | 0.68 | POLB (0.53) | POLBGPR55ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11425808 | 0.68 | POLB (0.58) | POLBGPR55MAPTKMT2ANPC1 | |
| SCHEMBL11426233 | 0.68 | GPR55 (0.63) | POLBGPR55ALDH1A1MAPTKMT2A | |
| SCHEMBL11492393 | 0.67 | POLB (0.57) | POLBGPR55ALDH1A1MAPTKMT2A | |
| SCHEMBL11062446 | 0.67 | POLB (0.57) | POLBGPR55ALDH1A1MAPTKMT2A | |
| SCHEMBL11036021 | 0.67 | POLB (0.57) | POLBGPR55ALDH1A1MAPTMCL1 | |
| SCHEMBL10705080 | 0.66 | POLB (0.59) | POLBGPR55ALDH1A1MAPTNPC1 | |
| SCHEMBL11062673 | 0.65 | POLB (0.50) | POLBGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4232043-A | HALO-, METHOXY-, METHYL- OR 4-NITRO PHENYL-SUBSTITUTED 2,6-DI(T-BUTYL) PHENOL | RIKER LABORATORIES, INC. (US) | 1980-11-04 | — | — | US | disclosed |
| US-4219501-A | Anti-inflammatory method | RIKER LABORATORIES, INC. (US) | 1980-08-26 | — | — | US | disclosed |
| US-4172151-A | 2,6-DI-TERT-BUTYL-PHENOL DERIVATIVES | RIKER LABORATORIES, INC. (US) | 1979-10-23 | — | — | US | disclosed |