Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | DRD3 | P35462 | 5/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071121 | 0.91 | DRD2 (0.53) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11066899 | 0.91 | HTR7 (0.50) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11073945 | 0.90 | DRD2 (0.58) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11065050 | 0.85 | DRD2 (0.51) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11068676 | 0.85 | KCNH2 (0.53) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11073453 | 0.85 | DRD2 (0.44) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11071326 | 0.85 | DRD2 (0.47) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11064850 | 0.84 | DRD2 (0.48) | DRD2DRD3DRD4CCR1HTR7 | |
| SCHEMBL11064025 | 0.82 | DRD2 (0.44) | DRD2DRD3DRD4HTR1AHTR2A | |
| SCHEMBL11071128 | 0.82 | DRD2 (0.48) | DRD2DRD3DRD4CCR1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |