Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070228 | 0.85 | MAOB (0.62) | MAOBMAOASLC6A2SLC6A4TMEM97 | |
| SCHEMBL10570629 | 0.84 | DRD2 (0.53) | TMEM97SIGMAR1ADRB2CHRM2CHRM4 | |
| SCHEMBL11068680 | 0.84 | ADRB2 (0.59) | MAOBMAOASLC6A2SLC6A4TMEM97 | |
| Oxalic Acid SCHEMBL11064085 | 0.82 | MAOB (0.60) | MAOBMAOASLC6A2SLC6A4TMEM97 | |
| SCHEMBL11071115 | 0.82 | ADRB2 (0.63) | MAOBMAOASLC6A2SLC6A4ADRB2 | |
| SCHEMBL11064029 | 0.80 | CHRM1 (0.63) | MAOBMAOASLC6A2SLC6A4ADRB2 | |
| SCHEMBL11063017 | 0.79 | MAOB (0.58) | MAOBMAOASLC6A2SLC6A4TMEM97 | |
| SCHEMBL11071523 | 0.79 | CHRM2 (0.65) | MAOBMAOASLC6A2SLC6A4SIGMAR1 | |
| SCHEMBL11068257 | 0.79 | ADRB2 (0.59) | MAOBMAOASLC6A2SLC6A4TMEM97 | |
| SCHEMBL11063325 | 0.74 | CHRM2 (0.53) | MAOBMAOACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |