Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 5/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1099798 | 0.83 | SLC18A3 (0.67) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL11684911 | 0.81 | SLC18A3 (0.62) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL9159777 | 0.81 | SLC18A3 (0.73) | SLC18A3DRD2MEN1KMT2A | |
| SCHEMBL23374659 | 0.76 | SLC18A3 (0.56) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL12447397 | 0.76 | SLC18A3 (0.56) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL12768109 | 0.76 | SLC18A3 (0.56) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL10600104 | 0.75 | SLC18A3 (1.00) | SLC18A3DRD2 | |
| SCHEMBL11027135 | 0.75 | SLC18A3 (0.69) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL1003503 | 0.74 | DRD2 (0.73) | SLC18A3DRD2MEN1KMT2ACARM1 | |
| SCHEMBL8104014 | 0.74 | DRD2 (0.68) | SLC18A3DRD2MEN1KMT2ACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |