Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678485 | 0.86 | KMT2A (0.48) | KMT2AUSP2TSHRHPGDCYP1A2 | |
| SCHEMBL7682322 | 0.84 | THRB (0.48) | KMT2AUSP2TSHRHPGDCYP1A2 | |
| SCHEMBL10920481 | 0.84 | TSHR (0.47) | KMT2AUSP2TSHRHPGDL3MBTL1 | |
| SCHEMBL11069408 | 0.83 | KMT2A (0.50) | KMT2AUSP2TSHRHPGDCYP3A4 | |
| SCHEMBL11087572 | 0.80 | KMT2A (0.42) | KMT2AUSP2TSHRL3MBTL1MAPT | |
| SCHEMBL11085284 | 0.80 | TSHR (0.49) | KMT2ATSHRHPGDL3MBTL1MAPT | |
| SCHEMBL11198068 | 0.79 | KMT2A (0.41) | KMT2AUSP2TSHRHPGDL3MBTL1 | |
| SCHEMBL11363402 | 0.78 | KMT2A (1.00) | KMT2AUSP2TSHRHPGDCYP1A2 | |
| SCHEMBL11090601 | 0.78 | KMT2A (0.40) | KMT2AUSP2TSHRHPGDCYP1A2 | |
| SCHEMBL11084402 | 0.78 | USP2 (0.52) | KMT2AUSP2TSHRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465843-A | ALKYLATION, SAPONIFICATION, DECARBOXYLATION, AND BENZOYLATION OF 3,S-SIETHOXYCARBONYL-4-METHYL-2-PYRROLE ACETATE | LABORATORIES PHARMEDICAL SA (LU) | 1984-08-14 | — | — | US | disclosed |