Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9453953 | 0.86 | RAB9A (0.66) | RAB9ASMN1; SMN2POLBMAPTALDH1A1 | |
| SCHEMBL5449567 | 0.86 | IDO1 (0.78) | IDO1SAE1UBA2RAB9APOLB | |
| SCHEMBL4104728 | 0.83 | SAE1 (0.76) | CYP2A6SAE1UBA2RAB9ASMN1; SMN2 | |
| SCHEMBL17956781 | 0.82 | TSHR (0.64) | IDO1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL11072625 | 0.81 | IDO1 (0.62) | IDO1SAE1UBA2SMN1; SMN2POLB | |
| SCHEMBL8956175 | 0.81 | IDO1 (0.66) | CYP2A6IDO1RAB9ASMN1; SMN2POLB | |
| SCHEMBL91062 | 0.80 | CYP2A6 (1.00) | CYP2A6IDO1MAPTALDH1A1HPGD | |
| SCHEMBL6295850 | 0.79 | ALDH1A1 (0.72) | IDO1RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL10514730 | 0.79 | IDO1 (0.68) | IDO1SAE1UBA2SMN1; SMN2MAPT | |
| SCHEMBL5445603 | 0.79 | SMN1; SMN2 (0.73) | RAB9ASMN1; SMN2POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |