Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 5/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29398608 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRBCHEACHENR4A2 | |
| SCHEMBL254822 | 0.83 | KDM4E (0.46) | ALDH1A1TSHRKDM4EHSD17B10NPC1 | |
| SCHEMBL358326 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4PIK3CAADRA2B | |
| Hydrochloric Acid SCHEMBL4332744 | 0.80 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP3A4PIK3CAADRA2B | |
| SCHEMBL29048096 | 0.78 | KDM4E (0.43) | ALDH1A1TSHRKDM4EHSD17B10NPC1 | |
| SCHEMBL10437707 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRBCHEACHENR4A2 | |
| SCHEMBL3789699 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRBCHEACHENR4A2 | |
| SCHEMBL3785150 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRBCHEACHENR4A2 | |
| SCHEMBL9627789 | 0.77 | CYP3A4 (0.50) | ALDH1A1TSHRBCHEACHECYP3A4 | |
| SCHEMBL2203933 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4PIK3CAADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744311-A | Synthesis method of bifenazate | MAISON CHEMICAL CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-103613600-A | Anilino podophyllotoxin derivative with anti-tumor activity and preparation method and application thereof | UNIV HUBEI TECHNOLOGY | 2014-03-05 | — | — | CN | claimed |
| EP-3959211-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS | BAYER AG (DE) | 2026-02-18 | — | — | EP | disclosed |
| EP-3958865-B1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES | BAYER AG (DE) | 2025-12-10 | — | — | EP | disclosed |
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2025-09-02 | — | — | US | disclosed |
| US-20250197391-A1 | METHODS OF SYNTHESIZING EGFR INHIBITORS | ANTARES THERAPEUTICS, INC. | 2025-06-19 | — | — | US | disclosed |
| US-20250136599-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2025-05-01 | — | — | US | disclosed |
| CN-119698415-A | Methods of synthesizing EGFR inhibitors | 蝎子疗法股份有限公司 | 2025-03-25 | — | — | CN | disclosed |
| EP-4499635-A1 | METHODS OF SYNTHESIZING EGFR INHIBITORS | Scorpion Therapeutics, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| US-20240408093-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. | 2024-12-12 | — | — | US | disclosed |
| CN-118852213-A | Pyrrole fused heterocyclic derivative and application thereof in medicine | 西藏海思科制药有限公司 | 2024-10-29 | — | — | CN | disclosed |
| US-4193937-A | DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4112100-A | INCREASING THE ENDOGENOUS PRODUCTION OF PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4096157-A | PIGMENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4085141-A | Process for the preparation of anilines meta-substituted by chlorine | BAYER AKTIENGESELLSCHAFT (DT) | 1978-04-18 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3989756-A | RANEY CATALYST, DEHALOGENATION INHIBITOR | NIPPON KAYAKU KABUSHIKI KAISHA (JA) | 1976-11-02 | — | — | US | disclosed |
| US-3965087-A | Trisazo dye containing a diphenylenesulfone structure | SAKAI CHEMICAL INDUSTRY COMPANY LTD. (JA) | 1976-06-22 | — | — | US | disclosed |
| US-3951941-A | POLYAZODYE | SAKAI CHEMICAL INDUSTRY COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12403135-B2 | 4H-pyrrolo[3,2-c]pyridin-4-one derivatives | EGFR, ERBB2, ERBB4 | ALDH1A1 1255/4885TSHR 2270/4885BCHE 4221/4885 |
| US-20250197391-A1 | METHODS OF SYNTHESIZING EGFR INHIBITORS | ERBB2, EGFR, ERBB3 | ALDH1A1 2417/4885TSHR 444/4885BCHE 4324/4885 |
| US-20240408093-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | FGFR3, FGFR1, ERBB3 | ALDH1A1 4423/4885TSHR 3022/4885BCHE 3034/4885 |
| US-20250136599-A1 | 4H-PYRROLO[3,2-C]PYRIDIN-4-ONE COMPOUNDS | CYP4B1, CYP2C19, PAH | ALDH1A1 245/4885TSHR 1609/4885BCHE 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.