Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29048096 | 0.95 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL16733990 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL197298 | 0.85 | SMN1; SMN2 (0.50) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL3236165 | 0.85 | RAB9A (0.50) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL2094513 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL1703057 | 0.83 | TAS1R3 (0.45) | KDM4EALDH1A1HSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL3837354 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL1307407 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL21027568 | 0.83 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL110638 | 0.83 | ALDH1A1 (0.52) | KDM4EALDH1A1HSD17B10MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022023027-A1 | NOVEL CHROMIUM-BASED CATALYTIC COMPOSITION AND ASSOCIATED METHOD FOR THE TRIMERISATION OF ETHYLENE TO HEXENE-1 | IFP Energies Nouvelles (FR) | 2022-02-03 | — | — | WO | claimed |
| CN-108623581-B | Method for preparing paninula compound | 中国海洋大学 | 2021-10-22 | — | — | CN | claimed |
| EP-2178373-B1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN INC (US) | 2013-01-23 | — | — | EP | claimed |
| EP-2536718-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | Icagen, Inc. (US) | 2012-12-26 | — | — | EP | claimed |
| US-8058274-B2 | Heterocycles as potassium channel modulators | ICAGEN, INC. (US) | 2011-11-15 | — | — | US | claimed |
| WO-2011102964-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2011-08-25 | — | — | WO | claimed |
| EP-2178373-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | Icagen, Inc. (US) | 2010-04-28 | — | — | EP | claimed |
| US-20090062290-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2009-03-05 | — | — | US | claimed |
| WO-2009026254-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | ICAGEN, INC. (US) | 2009-02-26 | — | — | WO | claimed |
| US-5475155-A | Reacting an alpha-haloketone with a phenolic-hydroxyl containing compound and a strong protonic acid; neutralization; dehydrohalogenation; dealkylation | THE DOW CHEMICAL COMPANY (US) | 1995-12-12 | — | — | US | claimed |
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | claimed |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| CN-120136692-A | Synthesis method of nemonoxacin malate intermediate 2, 4-difluoro-3-methoxy-1-benzoic acid | 浙江昌海制药有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120136692-A | Synthesis method of nemonoxacin malate intermediate 2, 4-difluoro-3-methoxy-1-benzoic acid | 浙江昌海制药有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120050872-A | X-shaped hole rapid filling electroplating process, device and electroplating liquid | 广东硕成科技股份有限公司 | 2025-05-27 | — | — | CN | disclosed |
| US-4542243-A | HALOALKYLATION, ETHERIFICATION, HYDRODEHALOGENATION, INSECTICIDES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1985-09-17 | — | — | US | disclosed |
| US-4538003-A | TREATMENT WITH MAGNESIUM OR ZINC ORGANOMETALLIC REAGENTS IN PRESENE OF A NICKEL BIDENTATE OR TRIDENTATE PHOSPHOROUS LIGAND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0066769-B1 | FUNGICIDES FOR THE PROTECTION OF MATERIAL | BAYER AG (DE) | 1985-07-31 | — | — | EP | disclosed |
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | disclosed |
| US-4057585-A | FROM 1,2,3-TRICHLOROBENZENE AND ALKALI METAL ALKOXIDE | SMITHKLINE CORPORATION (US) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062290-A1 | HETEROCYCLES AS POTASSIUM CHANNEL MODULATORS | KCNJ2, KCNK2, KCNK17 | KDM4E 1373/4885ALDH1A1 2150/4885HSD17B10 2434/4885 |
| US-12336981-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNMT, NNT | KDM4E 1401/4885ALDH1A1 984/4885HSD17B10 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.