Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032885 | 0.84 | BRD4 (0.51) | POLBGAAMAPK1LMNANPSR1 | |
| SCHEMBL9032721 | 0.83 | NPSR1 (0.43) | POLBGAAMAPK1LMNANPSR1 | |
| SCHEMBL11073784 | 0.82 | POLB (0.56) | POLBGAAMAPTRECQLKMT2A | |
| SCHEMBL11409293 | 0.77 | HPGD (0.57) | MAPTMAPK1LMNAKMT2ATSHR | |
| SCHEMBL3655855 | 0.77 | POLB (0.83) | POLBGAAMAPTLMNARECQL | |
| SCHEMBL11067691 | 0.75 | POLB (0.49) | POLBGAAMAPTLMNARECQL | |
| SCHEMBL23177789 | 0.72 | POLB (1.00) | POLBGAALMNAKMT2ANPSR1 | |
| SCHEMBL891915 | 0.72 | POLB (1.00) | POLBGAALMNAKMT2ANPSR1 | |
| SCHEMBL5843614 | 0.72 | POLB (1.00) | POLBGAALMNAKMT2ANPSR1 | |
| SCHEMBL4005026 | 0.72 | POLB (0.69) | POLBGAAMAPTRECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020293-B1 | STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |
| US-4309546-A | Piperidino pyrrolidinones | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0020293-A1 | Stabilising compounds, process for their preparation and compositions containing them | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |