SCHEMBL9032885

SCHEMBL9032885

COC(=O)C1CC(=O)N(C2CC(C)(C)NC(C)(C)C2)C1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.51
MAPK1 P28482 1/20 0.43
CA1 P00915 4/20 0.41
CA2 P00918 4/20 0.41
CA4 P22748 4/20 0.41
CA6 P23280 4/20 0.41
CA7 P43166 4/20 0.41
CA9 Q16790 4/20 0.41
CA13 Q8N1Q1 4/20 0.41
CA5B Q9Y2D0 3/20 0.41
GAA P10253 2/20 0.41
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11063994 0.84 POLB (0.56) MAPK1GAALMNAPOLBNPSR1
SCHEMBL11065362 0.83 BRD4 (0.55) BRD4CA1CA2CA4CA6
SCHEMBL9032721 0.82 NPSR1 (0.43) MAPK1CA1CA2CA4CA6
SCHEMBL11260515 0.81 BRD4 (0.49) BRD4CA1CA2CA4CA6
SCHEMBL17184777 0.81 BRD4 (0.62) BRD4CA1CA2CA4CA6
SCHEMBL11409293 0.79 HPGD (0.57) MAPK1ALDH1A1LMNAL3MBTL1HPGD
SCHEMBL11072919 0.78 BRD4 (0.49) BRD4CA1CA2CA4CA6
SCHEMBL1461817 0.78 POLB (0.59) BRD4GAAALDH1A1POLBNPSR1
SCHEMBL21575851 0.77 POLB (0.67) BRD4GAAALDH1A1POLBNPSR1
SCHEMBL21385730 0.77 POLB (0.67) BRD4GAAALDH1A1POLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020293-B1 STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-05-23 EP claimed
US-4309546-A Piperidino pyrrolidinones CIBA-GEIGY CORPORATION (US) 1982-01-05 US claimed
EP-0020293-A1 Stabilising compounds, process for their preparation and compositions containing them CIBA-GEIGY AG (CH) 1980-12-10 EP claimed
EP-0410970-B1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA ELF (US) 1996-08-14 EP disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5300545-A Mixing with a N-(2,2,6,6-tetraalkyl-4-piperidinyl)amide-hydrazides stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-05 US disclosed
EP-0516192-A2 Reactive hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-12-02 EP disclosed
US-5101033-A Piperidinyl-N-aminooxamides ATOCHEM NORTH AMERICA, INC. (US) 1992-03-31 US disclosed
EP-0410970-A4 REACTIVE HINDERED AMINE LIGHT STABILIZERS 1991-07-31 EP disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
EP-0410970-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS. ATOCHEM NORTH AMERICA (US) 1991-02-06 EP disclosed
US-4983738-A For polymers ATOCHEM NORTH AMERICA, INC. (US) 1991-01-08 US disclosed
WO-1990009408-A1 REACTIVE HINDERED AMINE LIGHT STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed
EP-0020293-B1 STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1984-05-23 EP disclosed
US-4309546-A Piperidino pyrrolidinones CIBA-GEIGY CORPORATION (US) 1982-01-05 US disclosed
EP-0020293-A1 Stabilising compounds, process for their preparation and compositions containing them CIBA-GEIGY AG (CH) 1980-12-10 EP disclosed