Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28378581 | 0.81 | BACE1 (0.50) | HPGDTDP1ALDH1A1TSHRBACE1 | |
| SCHEMBL9032885 | 0.79 | BRD4 (0.51) | HPGDL3MBTL1ALDH1A1MAPK1LMNA | |
| SCHEMBL11063994 | 0.77 | POLB (0.56) | MAPTTSHRMAPK1LMNAKMT2A | |
| SCHEMBL6222371 | 0.76 | HPGD (0.66) | HPGDTDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL11273367 | 0.74 | SMN1; SMN2 (0.45) | HPGDTDP1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL27758268 | 0.74 | HPGD (0.62) | HPGDTDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL16695405 | 0.73 | KMT2A (0.67) | HPGDTDP1ATML3MBTL1ALDH1A1 | |
| SCHEMBL6758990 | 0.71 | ALDH1A1 (0.51) | HPGDTDP1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL3160414 | 0.71 | TSHR (0.46) | ALDH1A1TSHRBACE1SMN1; SMN2 | |
| SCHEMBL15709720 | 0.70 | SMN1; SMN2 (0.53) | L3MBTL1HTTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020293-A1 | Stabilising compounds, process for their preparation and compositions containing them | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |