Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114146 | 0.92 | SNCA (0.55) | SNCACA2CA12CA1CA9 | |
| SCHEMBL9194040 | 0.83 | SNCA (0.50) | SNCACA2CA12CA1CA9 | |
| SCHEMBL11028193 | 0.83 | TSHR (0.57) | SNCACA2CA12CA1CA9 | |
| SCHEMBL809030 | 0.81 | ALDH1A1 (0.60) | ALDH1A1NPC1MAPTRAB9ACYP1A2 | |
| Hydrochloric Acid SCHEMBL11060114 | 0.81 | ALDH1A1 (0.60) | ALDH1A1NPC1MAPTRAB9ACYP1A2 | |
| Bicarbonate SCHEMBL7292653 | 0.81 | SNCA (0.64) | SNCACA2ALDH1A1KAT6ALMNA | |
| Hydrochloric Acid SCHEMBL3441755 | 0.81 | SNCA (0.62) | SNCACA2CA1CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30139547 | 0.81 | SNCA (0.62) | SNCACA2CA1CA9ALDH1A1 | |
| Propionic Acid SCHEMBL28042013 | 0.80 | SNCA (0.55) | SNCAALDH1A1KAT6ALMNAHTT | |
| SCHEMBL11059512 | 0.80 | ALDH1A1 (0.58) | ALDH1A1NPC1MAPTRAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004740-B1 | A PENICILLIN SALT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | BEECHAM GROUP PLC (GB) | 1982-01-20 | — | — | EP | claimed |
| EP-0004740-A2 | A penicillin salt, process for its preparation and pharmaceutical compositions containing it | BEECHAM GROUP PLC (GB) | 1979-10-17 | — | — | EP | claimed |
| US-4481209-A | TALAMPICILLIN NAPSYLATE | BEECHAM GROUP LIMITED (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0004740-B1 | A PENICILLIN SALT, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT | BEECHAM GROUP PLC (GB) | 1982-01-20 | — | — | EP | disclosed |
| EP-0004740-A2 | A penicillin salt, process for its preparation and pharmaceutical compositions containing it | BEECHAM GROUP PLC (GB) | 1979-10-17 | — | — | EP | disclosed |