Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434533 | 0.84 | HRH1 (0.53) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL19459487 | 0.82 | HRH1 (0.57) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL726645 | 0.78 | HRH1 (0.73) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL3169642 | 0.78 | HRH1 (0.50) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL2841394 | 0.76 | HRH1 (0.77) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL4413800 | 0.76 | HRH1 (0.77) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL725306 | 0.76 | HRH1 (0.77) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL14273406 | 0.76 | HRH1 (0.53) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL10397794 | 0.74 | HRH1 (0.52) | HRH1NAAALOXL2HRH3HRH4 | |
| SCHEMBL9519950 | 0.74 | HRH1 (0.52) | HRH1NAAALOXL2HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482663-A | Rubber compositions comprising a siliceous filler in combination with an organosulfur substituted pyridine promotor | PHILLIPS PETROLEUM COMPANY (US) | 1984-11-13 | — | — | US | disclosed |