Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 10/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 5/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11068549 | 0.99 | SLC6A2 (0.60) | SLC6A2SLC6A4MAOBTMEM97SIGMAR1 | |
| SCHEMBL11066530 | 0.92 | MAOB (0.62) | SLC6A2SLC6A4MAOBTMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11065081 | 0.91 | MAOB (0.61) | SLC6A2SLC6A4MAOBTMEM97SIGMAR1 | |
| SCHEMBL7405352 | 0.83 | SLC6A2 (0.67) | SLC6A2SLC6A4MAOBTMEM97SIGMAR1 | |
| SCHEMBL11095268 | 0.81 | POLB (0.58) | — | |
| Hydrochloric Acid SCHEMBL10571187 | 0.80 | DRD2 (0.62) | TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL11065329 | 0.80 | PARP1 (0.50) | SLC6A4MAOBMAOAHRH3 | |
| Hydrochloric Acid SCHEMBL11070340 | 0.78 | SLC2A1 (0.58) | SLC6A4MAOBSIGMAR1MAOAHRH3 | |
| SCHEMBL11345831 | 0.78 | PDE3B (0.50) | MAOBACHEBCHEMAOAHRH3 | |
| SCHEMBL11084557 | 0.78 | ACHE (0.58) | MAOBACHEBCHEMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |