Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838666 | 0.84 | KMT2A (0.53) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL1255010 | 0.80 | CA12 (0.55) | KMT2ANPC1RAB9AMEN1CA12 | |
| SCHEMBL4333356 | 0.78 | KMT2A (0.55) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL5933377 | 0.78 | TDP1 (0.66) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL1520687 | 0.77 | ALOX5 (0.65) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL1206390 | 0.75 | AOC3 (0.55) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL2018404 | 0.75 | TDP1 (0.52) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL7228409 | 0.75 | MEN1 (0.61) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL6138832 | 0.75 | KMT2A (0.52) | KMT2ANPC1RAB9ATDP1MEN1 | |
| SCHEMBL1520363 | 0.75 | KMT2A (0.59) | KMT2ANPC1RAB9ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487952-A | CARBONYLATION OF AROMATIC NITRO COMPOUNDS | ANIC S.P.A. (IT) | 1984-12-11 | — | — | US | disclosed |