Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955098 | 0.88 | KMT2A (0.49) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL4325564 | 0.83 | ESR1 (0.52) | KMT2ATDP1TAAR1ALDH1A1CYP2C19 | |
| SCHEMBL5933377 | 0.82 | TDP1 (0.66) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL1520687 | 0.80 | ALOX5 (0.65) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL30443271 | 0.79 | KMT2A (0.53) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL6875797 | 0.79 | TAAR1 (0.46) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL28028786 | 0.79 | ALOX5 (0.54) | KMT2AALOX5HDAC3LMNAOPRM1 | |
| SCHEMBL2018404 | 0.78 | TDP1 (0.52) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL7228409 | 0.78 | MEN1 (0.61) | KMT2ATDP1MEN1NPC1RAB9A | |
| SCHEMBL1206390 | 0.78 | AOC3 (0.55) | KMT2ATDP1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |