Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
| ▸ | FYN | P06241 | 2/20 | 0.53 |
| ▸ | MMP9 | P14780 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28080618 | 0.82 | CA12 (0.55) | LMNACA2ALDH1A1TDP1KDM4E | |
| Catechol SCHEMBL10785335 | 0.81 | CA2 (0.56) | LMNACA2ALDH1A1ALOX15TDP1 | |
| SCHEMBL9694538 | 0.81 | ALDH1A1 (0.52) | LMNACA2ALDH1A1ALOX15TDP1 | |
| Biphenyl SCHEMBL8163372 | 0.79 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4EMAPTSMN1; SMN2 | |
| Hydroquinone SCHEMBL483602 | 0.78 | ESR1 (0.50) | LMNACA2ALDH1A1ALOX15HPGD | |
| Catechol SCHEMBL27968623 | 0.77 | ALDH1A1 (0.67) | LMNACA2ALDH1A1ALOX15TDP1 | |
| Catechol SCHEMBL11558329 | 0.77 | CA2 (0.50) | LMNACA2ALDH1A1ALOX15TDP1 | |
| Catechol SCHEMBL9427360 | 0.76 | ALDH1A1 (0.77) | LMNACA2ALDH1A1ALOX15TDP1 | |
| Catechol SCHEMBL10919762 | 0.76 | — | — | |
| Resorcinol SCHEMBL443226 | 0.75 | ALDH1A1 (0.57) | LMNACA2ALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457997-A | CROTONIC ACID-VINYL ACETATE BINDER | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| US-4273850-A | 2,5-DIALKOXY-4-ARYLMERCAPTOBENZENE DIAZONIUM SALTS AND A HYDROXYNAPHTHALENE DISULFONAMIDE COUPLER | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-06-16 | — | — | US | disclosed |