Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071631 | 0.90 | DRD4 (0.49) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11067634 | 0.90 | DRD4 (0.51) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11068716 | 0.89 | SLC18A3 (0.42) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11066890 | 0.89 | ABCB1 (0.57) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL11064628 | 0.88 | ABCB1 (0.57) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11060483 | 0.86 | DRD4 (0.51) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11070246 | 0.82 | DRD4 (0.55) | DRD4DRD2ADRB2ADRB1ALDH1A1 | |
| SCHEMBL11066891 | 0.79 | ABCB1 (0.61) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| SCHEMBL11065039 | 0.79 | DRD4 (0.60) | DRD4ABCB1DRD2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL11067627 | 0.78 | ABCB1 (0.61) | DRD4ABCB1DRD2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |