Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11071627 | 0.97 | ABCB1 (0.58) | DRD4DRD2ABCB1KMT2AMEN1 | |
| SCHEMBL11066891 | 0.93 | ABCB1 (0.61) | DRD4DRD2ABCB1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL11067627 | 0.91 | ABCB1 (0.61) | DRD4DRD2ABCB1KMT2AMEN1 | |
| SCHEMBL11066890 | 0.90 | ABCB1 (0.57) | DRD4DRD2ABCB1KMT2AMEN1 | |
| SCHEMBL11061136 | 0.89 | KCNH2 (0.56) | DRD4DRD2ABCB1ADRB2ADRB1 | |
| SCHEMBL11067274 | 0.89 | ABCB1 (0.48) | DRD4DRD2ABCB1KMT2AMEN1 | |
| SCHEMBL11073897 | 0.88 | ABCB1 (0.62) | DRD4DRD2ABCB1KMT2AMEN1 | |
| SCHEMBL11071631 | 0.88 | DRD4 (0.49) | DRD4DRD2ABCB1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL11064628 | 0.88 | ABCB1 (0.57) | DRD4DRD2ABCB1KMT2AMEN1 | |
| Oxalic Acid SCHEMBL11060455 | 0.86 | ABCB1 (0.61) | DRD4DRD2ABCB1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | claimed |
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |