Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 7/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066890 | 0.98 | ABCB1 (0.57) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL11067627 | 0.90 | ABCB1 (0.61) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL11071627 | 0.90 | ABCB1 (0.58) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| Oxalic Acid SCHEMBL11068715 | 0.89 | KCNH2 (0.50) | ABCB1ADRB2ADRB1ADRB3 | |
| SCHEMBL11064147 | 0.88 | DRD4 (0.46) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| SCHEMBL11066891 | 0.88 | ABCB1 (0.61) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| SCHEMBL11065039 | 0.88 | DRD4 (0.60) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| SCHEMBL11064919 | 0.86 | ADRB2 (0.51) | ABCB1DRD4ADRB2ADRB1ADRB3 | |
| Oxalic Acid SCHEMBL11060455 | 0.86 | ABCB1 (0.61) | ABCB1DRD4DRD2ADRB2ADRB1 | |
| SCHEMBL11073897 | 0.83 | ABCB1 (0.62) | ABCB1DRD4DRD2ADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |