Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064304 | 0.79 | PDE3B (0.46) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL11058595 | 0.77 | PDE3B (0.35) | ALDH1A1PDE3BPDE3ALMNAMEN1 | |
| SCHEMBL11067714 | 0.77 | PYGL (0.38) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11069573 | 0.77 | RAF1 (0.40) | ALDH1A1TP53POLBMEN1KMT2A | |
| SCHEMBL11060616 | 0.74 | PDE3B (0.52) | PDE3BPDE3ACREBBP | |
| SCHEMBL11067577 | 0.74 | PDE3B (0.38) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL27961997 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TP53SMN1; SMN2CREBBPPOLB | |
| SCHEMBL11061198 | 0.72 | MEN1 (0.38) | POLBLMNAMEN1KMT2A | |
| SCHEMBL11064332 | 0.72 | PDE3B (0.38) | ALDH1A1PDE3BPDE3A | |
| SCHEMBL11067554 | 0.72 | PDE3B (0.73) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |