Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29021078 | 0.87 | ALDH1A1 (0.44) | MC5RMAPK1ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL30504155 | 0.85 | MAPK1 (0.45) | MC5RMAPK1TOP2ATOP2BCA12 | |
| SCHEMBL3044020 | 0.85 | MAPK1 (0.45) | MC5RMAPK1TOP2ATOP2BHIF1A | |
| SCHEMBL30587139 | 0.85 | MAPK1 (0.45) | MC5RMAPK1TOP2ATOP2BHIF1A | |
| SCHEMBL3045619 | 0.85 | MAPK1 (0.45) | MC5RMAPK1TOP2ATOP2BCA12 | |
| SCHEMBL136100 | 0.85 | ALDH1A1 (0.46) | MC5RMAPK1ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL7638103 | 0.82 | TOP2A (0.40) | MC5RMAPK1TOP2ATOP2BCA12 | |
| SCHEMBL3923568 | 0.81 | CYP1A2 (0.52) | CA12CA2CA3CA4CA6 | |
| SCHEMBL29871049 | 0.81 | HTR2A (0.41) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 | |
| SCHEMBL1826097 | 0.81 | HTR2A (0.41) | ALDH1A1HSD17B10CYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448935-A | CHLORO, BROMO OR HYDROXY AROMATIC CROSSLINKING AGENTS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1984-05-15 | — | — | US | claimed |