⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16944043 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL19091449 | 0.81 | MEN1 (0.34) | — | |
| SCHEMBL3280248 | 0.79 | — | — | |
| SCHEMBL635332 | 0.79 | — | — | |
| SCHEMBL4071999 | 0.79 | — | — | |
| SCHEMBL7438406 | 0.76 | — | — | |
| SCHEMBL1048076 | 0.76 | — | — | |
| SCHEMBL2745822 | 0.76 | — | — | |
| SCHEMBL13072431 | 0.76 | — | — | |
| SCHEMBL10903390 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 657 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016863-A2 | METHODS AND USES OF CYTOCHROME P450 INHIBITORS | ANGION BIOMEDICA CORP. (US) | 2011-02-10 | — | — | WO | claimed |
| US-7879852-B2 | such as (4S)-1-{[(3S,4R)-1-tert-butyl-4-(2,4-difluorophenyl)pyrrolidine-3-yl]carbonyl}-4-[(4,4-dimethylcyclohexyl)(2,2-dimethylpropanoyl)amino]-N,N-dimethyl-L-prolineamide, used for the treatment of obesity, diabetes, inflammation and erectile dysfunction | LG LIFE SCIENCES LTD. (KR) | 2011-02-01 | — | — | US | claimed |
| US-20090298829-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2009-12-03 | — | — | US | claimed |
| WO-2008007930-A9 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2009-04-02 | — | — | WO | claimed |
| EP-2041120-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2009-04-01 | — | — | EP | claimed |
| WO-2008007930-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2008-01-17 | — | — | WO | claimed |
| US-5777105-A | Process for the preparation of imidazolyl macrolide immunosuppressants | MERCK & CO., INC. (US) | 1998-07-07 | — | — | US | claimed |
| EP-0848717-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOLYL MACROLIDE IMMUNOSUPPRESSANTS | Merck & Co., Inc. (US) | 1998-06-24 | — | — | EP | claimed |
| WO-1997008182-A1 | PROCESS FOR THE PREPARATION OF IMIDAZOLYL MACROLIDE IMMUNOSUPPRESSANTS | MERCK & CO., INC. (US) | 1997-03-06 | — | — | WO | claimed |
| JP-11271306-A | — | — | None | — | — | JP | disclosed |
| US-20240368073-A1 | AMINE-BORANES AS BIFUNCTIONAL REAGENTS FOR DIRECT AMIDATION OF CARBOXYLIC ACIDS | PURDUE RESEARCH FOUNDATION (US) | 2024-11-07 | — | — | US | disclosed |
| US-12071393-B2 | Amine-boranes as bifunctional reagents for direct amidation of carboxylic acids | PURDUE RESEARCH FOUNDATION (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240238296-A1 | METHODS OF REGULATING BCL11A EXPRESSION AND TREATMENT OF BCL11A-MEDIATED DISORDERS | FULCRUM THERAPEUTICS INC (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240226107-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | HAINAN SIMCERE ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-4325836-A | Novel titanium halide containing catalyst | STAUFFER CHEMICAL COMPANY (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0044445-A2 | Titanium halide containing catalyst | STAUFFER CHEMICAL COMPANY (US) | 1982-01-27 | — | — | EP | disclosed |
| US-4312782-A | COORDINATION CATALYST FOR POLYMERIZATION OF ALPHA OLEFINS | STAUFFER CHEMICAL COMPANY (US) | 1982-01-26 | — | — | US | disclosed |
| EP-0043185-A1 | Method for production of titanium halide catalyst component, catalyst system including such component, and polymerization of alpha-olefins using such system | STAUFFER CHEMICAL COMPANY (US) | 1982-01-06 | — | — | EP | disclosed |
| EP-0040711-A1 | Titanium halide catalyst for polymerization | STAUFFER CHEMICAL COMPANY (US) | 1981-12-02 | — | — | EP | disclosed |
| US-4141992-A | Cycloalkylcarboxyamidines and halobenzamidines as anti-amebic agents | AMERICAN CYANAMID COMPANY (US) | 1979-02-27 | — | — | US | disclosed |