Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13959699 | 0.89 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL29573523 | 0.81 | TSHR (0.62) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL3766146 | 0.81 | TSHR (0.62) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL7891792 | 0.79 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL13959697 | 0.77 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL17595662 | 0.76 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Pyrene SCHEMBL2125072 | 0.74 | TSHR (0.65) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Fluorene SCHEMBL28767808 | 0.74 | TNF (0.44) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL13959695 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| Fluorene SCHEMBL28443999 | 0.73 | MAOA (0.59) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170077416-A1 | COMPOUND, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY | SAMSUNG SDI CO., LTD. (KR) | 2017-03-16 | — | — | US | disclosed |
| EP-0042659-B1 | 5,6,6A,7-TETRAHYDRO-4H-DIBENZ(DE,G)ISOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1984-08-29 | — | — | EP | disclosed |
| US-4425350-A | 5,6,6a,7-Tetrahydro-4H-dibenz(de,g)-isoquinoline derivatives, and their use for treating central nervous system disorders | WARNER-LAMBERT COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
| EP-0042659-A1 | 5,6,6a,7-Tetrahydro-4H-dibenz(de,g)isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170077416-A1 | COMPOUND, ORGANIC OPTOELECTRONIC DIODE COMPRISING SAME, AND DISPLAY | OR10J3, OR51E2, ODC1 | ALDH1A1 28/4885KDM4E 2866/4885HPGD 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.