Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 3/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | MMP13 | P45452 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637461 | 0.91 | CA1 (0.53) | PTGER4MMP13MMP8CA1CA2 | |
| SCHEMBL28493526 | 0.78 | ALDH1A1 (0.52) | MMP13MMP8CA1CA2MMP1 | |
| SCHEMBL28494294 | 0.74 | CA1 (0.60) | ACLYMMP13MMP8CA1CA2 | |
| SCHEMBL19165774 | 0.72 | HPGD (0.63) | ACLYCA1CA2LMNANPC1 | |
| SCHEMBL27482443 | 0.72 | CA1 (0.53) | ACLYMMP13MMP8CA1CA2 | |
| SCHEMBL11094513 | 0.71 | CA1 (0.45) | HDAC1MMP13MMP8CA1CA2 | |
| SCHEMBL10197486 | 0.71 | LMNA (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3936649 | 0.71 | CA1 (0.56) | ACLYMMP13MMP8CA1CA2 | |
| Biphenyl SCHEMBL27677322 | 0.71 | TSHR (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL5931096 | 0.71 | CA1 (0.60) | MMP13MMP8CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428956-A | GLYCOLATE OXIDASE INHIBITORS | MERCK & CO., INC. (US) | 1984-01-31 | — | — | US | disclosed |