Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073267 | 0.78 | SLC6A2 (0.49) | HRH1HTR2CSLC6A2HTR1ASLC6A3 | |
| SCHEMBL11064624 | 0.77 | HRH1 (0.50) | HRH1HTR2CSLC6A2HTR1ASLC6A3 | |
| SCHEMBL11073820 | 0.76 | KDM4E (0.46) | — | |
| Hydrochloric Acid SCHEMBL11065701 | 0.76 | HRH1 (0.49) | HRH1HTR2CSLC6A2HTR1ASLC6A3 | |
| SCHEMBL83377 | 0.73 | HRH1 (0.57) | HRH1HTR2CSLC6A2HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL473008 | 0.72 | HRH1 (0.55) | HRH1HTR2CSLC6A2HTR1ASLC6A3 | |
| SCHEMBL5473677 | 0.71 | HRH1 (0.58) | HRH1SLC6A2HTR1ASLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL29863150 | 0.70 | HRH1 (0.42) | HRH1SLC6A2HTR1ASLC6A3CHRM3 | |
| Hydrochloric Acid SCHEMBL5460821 | 0.70 | HRH1 (0.57) | HRH1SLC6A2HTR1ASLC6A3SLC6A4 | |
| SCHEMBL11068948 | 0.70 | HRH1 (0.49) | HRH1HTR2CSLC6A2HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |