Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.46 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.46 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.46 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11065701 | 0.99 | HRH1 (0.49) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| SCHEMBL11068619 | 0.82 | KDM4E (0.45) | SOS1KCNH2 | |
| Hydrochloric Acid SCHEMBL11067172 | 0.81 | SMN1; SMN2 (0.46) | SOS1KCNH2 | |
| SCHEMBL11064997 | 0.77 | HRH1 (0.44) | HRH1SOS1HTR2CSLC6A2SLC6A4 | |
| SCHEMBL11063126 | 0.75 | IKBKB (0.68) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| SCHEMBL1229572 | 0.74 | HRH1 (0.47) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| Hydrochloric Acid SCHEMBL71850 | 0.73 | HRH1 (0.46) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| SCHEMBL3117182 | 0.73 | SLC6A4 (0.46) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| Hydrochloric Acid SCHEMBL7452746 | 0.73 | IKBKB (0.66) | HRH1ROCK1ROCK2PRKACAPRKCD | |
| Hydrochloric Acid SCHEMBL11065086 | 0.73 | HRH3 (0.36) | SOS1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |