Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.52 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065027 | 1.00 | SOAT2 (0.52) | SOAT2SOAT1AKR1C3NR1H4HDAC11 | |
| SCHEMBL11070282 | 0.97 | SOAT2 (0.52) | SOAT2SOAT1AKR1C3NR1H4HDAC11 | |
| SCHEMBL11070287 | 0.97 | SOAT2 (0.52) | SOAT2SOAT1AKR1C3NR1H4HDAC11 | |
| SCHEMBL30012465 | 0.89 | HDAC11 (0.58) | AKR1C3NR1H4HDAC11HDAC8STS | |
| SCHEMBL6330083 | 0.89 | HDAC11 (0.58) | AKR1C3NR1H4HDAC11HDAC8STS | |
| SCHEMBL21940532 | 0.89 | HDAC11 (0.58) | AKR1C3NR1H4HDAC11HDAC8STS | |
| SCHEMBL6330053 | 0.89 | HDAC11 (0.58) | AKR1C3NR1H4HDAC11HDAC8STS | |
| SCHEMBL6332453 | 0.89 | HDAC11 (0.58) | AKR1C3NR1H4HDAC11HDAC8STS | |
| SCHEMBL11076556 | 0.89 | SOAT2 (0.49) | SOAT2SOAT1AKR1C3HDAC11HDAC8 | |
| SCHEMBL11076560 | 0.89 | SOAT2 (0.49) | SOAT2SOAT1AKR1C3HDAC11HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |