Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | F7 | P08709 | 3/20 | 0.42 |
| ▸ | F3 | P13726 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076556 | 1.00 | SOAT2 (0.49) | SOAT2SOAT1HDAC11HDAC8PPARA | |
| SCHEMBL11065030 | 0.89 | SOAT2 (0.52) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11065027 | 0.89 | SOAT2 (0.52) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11070282 | 0.86 | SOAT2 (0.52) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11070287 | 0.86 | SOAT2 (0.52) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11063964 | 0.86 | PPARA (0.47) | SOAT2SOAT1HDAC11HDAC8PPARA | |
| SCHEMBL11063961 | 0.86 | PPARA (0.47) | SOAT2SOAT1HDAC11HDAC8PPARA | |
| SCHEMBL11063612 | 0.85 | SOAT2 (0.48) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11063615 | 0.85 | SOAT2 (0.48) | SOAT2SOAT1HDAC11HDAC8EPHX2 | |
| SCHEMBL11309047 | 0.85 | SOAT2 (0.47) | SOAT2SOAT1PPARAEPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |