Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 11/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065039 | 0.89 | DRD4 (0.60) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| Oxalic Acid SCHEMBL11071627 | 0.87 | ABCB1 (0.58) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11061136 | 0.85 | KCNH2 (0.56) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11066891 | 0.82 | ABCB1 (0.61) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL10570390 | 0.82 | MAPT (0.56) | ABCB1MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL10570172 | 0.81 | MAPT (0.55) | ABCB1MEN1KMT2AKCNH2 | |
| SCHEMBL11062798 | 0.80 | CHRM2 (0.60) | ADRB2ADRB1DRD4DRD2KCNH2 | |
| Oxalic Acid SCHEMBL11067627 | 0.80 | ABCB1 (0.61) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11066992 | 0.80 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL11066890 | 0.79 | ABCB1 (0.57) | ABCB1ADRB2ADRB1ADRB3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |