Pyrrole

Pyrrole

SCHEMBL11065072

CCC(CC)(C(=O)O)P(=O)(O)O.c1cc[nH]c1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.33
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
GGPS1 O95749 1/20 0.31
LMNA P02545 1/20 0.30
GRM2 Q14416 1/20 0.30
GRM3 Q14832 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282438 0.85 FDPS (0.37) FDPSMEN1ALDH1A1KMT2AGGPS1
Hydrochloric Acid SCHEMBL4158783 0.83 FDPS (0.36) FDPSMEN1ALDH1A1KMT2AGGPS1
SCHEMBL2298232 0.83 FDPS (0.36) FDPSMEN1ALDH1A1KMT2AGGPS1
Ether SCHEMBL9377681 0.76 FDPS (0.31) FDPSALDH1A1TSHR
SCHEMBL7528777 0.76 FDPS (0.31) FDPS
SCHEMBL28156893 0.75 FDPS (0.33) FDPSGGPS1
Acrylic Acid SCHEMBL28624579 0.74 LMNA (0.40) FDPSALDH1A1TSHRLMNA
SCHEMBL6505412 0.74 FDPS (0.46) FDPSGGPS1
SCHEMBL870763 0.74 TSHR (0.39) FDPSMEN1ALDH1A1TSHRKMT2A
SCHEMBL7528768 0.72 CYP2D6 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4444770-A HYPOTENSIVE, DIURETIC BAYER AKTIENGESELLSCHAFT (DE) 1984-04-24 US disclosed