SCHEMBL11065102

SCHEMBL11065102

CC(C)OC1=CC(=O)C(C(=O)O)C(C)C1

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11059475 0.85 ALDH1A1 (0.50) ALDH1A1MAPK1
SCHEMBL8080611 0.73 ALDH1A1 (0.41) ALDH1A1MAPK1
SCHEMBL11066152 0.71
SCHEMBL8620995 0.70 ALDH1A1 (0.34) ALDH1A1
SCHEMBL11387249 0.70 BRD4 (0.31)
SCHEMBL15295671 0.62 ALDH1A1 (0.49) ALDH1A1MAPK1
SCHEMBL6844884 0.60 OPRD1 (0.46)
SCHEMBL2014580 0.59 MAPK1 (0.51) ALDH1A1MAPK1KMT2A
SCHEMBL8907400 0.59 ALDH1A1 (0.61) ALDH1A1MAPK1
SCHEMBL17970719 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4432378-A ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS FRITZSCHE, DODGE & OLCOTT, INC. (US) 1984-02-21 US disclosed
US-4326996-A FOR PERFUMES FRITZSCHE DODGE & OLCOTT INC. (US) 1982-04-27 US disclosed