Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621854 | 0.87 | HCRTR2 (0.45) | HCRTR1HCRTR2TSHRCYP2C19ALDH1A1 | |
| SCHEMBL21538635 | 0.78 | ALDH1A1 (0.50) | EHMT2MEN1KMT2ATSHRHPGD | |
| SCHEMBL11062654 | 0.78 | PTGS1 (0.40) | MEN1KMT2ACYP2C19 | |
| SCHEMBL8094843 | 0.77 | EHMT2 (0.45) | HCRTR1HCRTR2EHMT2MEN1KMT2A | |
| SCHEMBL17154894 | 0.77 | GBA1 (0.43) | — | |
| SCHEMBL7273490 | 0.75 | F2 (0.37) | HCRTR2EHMT2TSHRHPGDCYP3A4 | |
| SCHEMBL23556843 | 0.75 | GBA1 (0.44) | MEN1KMT2ACYP2C19 | |
| SCHEMBL6997539 | 0.75 | GBA1 (0.46) | MEN1KMT2A | |
| SCHEMBL24338282 | 0.75 | GBA1 (0.44) | MEN1KMT2ACYP2C19 | |
| SCHEMBL6997546 | 0.75 | GBA1 (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | claimed |
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |