Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CDC25C | P30307 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 4/20 | 0.49 |
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | FABP4 | P15090 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641739 | 0.88 | HPGD (0.48) | ALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL11069327 | 0.88 | SOAT2 (0.49) | EPHX2SOAT2SOAT1ALDH1A1F7 | |
| SCHEMBL11065936 | 0.88 | SOAT2 (0.49) | EPHX2SOAT2SOAT1ALDH1A1F7 | |
| SCHEMBL11065929 | 0.88 | SOAT2 (0.49) | EPHX2SOAT2SOAT1ALDH1A1F7 | |
| SCHEMBL11069324 | 0.88 | SOAT2 (0.49) | EPHX2SOAT2SOAT1ALDH1A1F7 | |
| SCHEMBL11072836 | 0.85 | SOAT2 (0.49) | EPHX2SOAT2SOAT1F7F3 | |
| SCHEMBL11072831 | 0.85 | SOAT2 (0.49) | EPHX2SOAT2SOAT1F7F3 | |
| SCHEMBL11302752 | 0.85 | EPHX2 (0.48) | EPHX2SOAT2SOAT1F7F3 | |
| SCHEMBL11067757 | 0.81 | SOAT2 (0.45) | EPHX2SOAT2SOAT1F7F3 | |
| SCHEMBL11067756 | 0.81 | SOAT2 (0.45) | EPHX2SOAT2SOAT1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |