Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 6/20 | 0.46 |
| ▸ | F3 | P13726 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.46 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.46 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065936 | 1.00 | SOAT2 (0.49) | SOAT2SOAT1CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL11069324 | 1.00 | SOAT2 (0.49) | SOAT2SOAT1CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL11065929 | 1.00 | SOAT2 (0.49) | SOAT2SOAT1CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL11072836 | 0.97 | SOAT2 (0.49) | SOAT2SOAT1CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL11072831 | 0.97 | SOAT2 (0.49) | SOAT2SOAT1CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL9780647 | 0.89 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1CNR2ALDH1A1PTGS1 | |
| SCHEMBL168558 | 0.88 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1CNR1CNR2ALDH1A1 | |
| SCHEMBL11065271 | 0.88 | EPHX2 (0.50) | SOAT2SOAT1EPHX2FAAHF7 | |
| SCHEMBL4730302 | 0.86 | PTGS2 (0.51) | CYSLTR2CYSLTR1HPGDTSHRPTGS1 | |
| SCHEMBL11067757 | 0.86 | SOAT2 (0.45) | SOAT2SOAT1EPHX2FAAHF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |