Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | CD40 | P25942 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063808 | 0.91 | APEX1 (0.54) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11049641 | 0.89 | ENPP2 (0.46) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11055558 | 0.85 | ENPP2 (0.43) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11050005 | 0.85 | APEX1 (0.53) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL9145883 | 0.85 | APEX1 (0.64) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11060526 | 0.84 | APEX1 (0.51) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11087743 | 0.84 | APEX1 (0.51) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11065104 | 0.84 | TIMP3 (0.42) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11049881 | 0.84 | APEX1 (0.57) | APEX1ENPP2CASP6CTDSP1MEN1 | |
| SCHEMBL11057878 | 0.83 | APEX1 (0.55) | APEX1ENPP2CASP6CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |