Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MLYCD | O95822 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071683 | 0.84 | PLK1 (0.56) | L3MBTL1MLYCDNAAACA2PLK1 | |
| SCHEMBL11074814 | 0.83 | PLK1 (0.53) | L3MBTL1MLYCDNAAACA2PLK1 | |
| SCHEMBL11071146 | 0.83 | NPC1 (0.55) | L3MBTL1MLYCDNAAAPLK1MEN1 | |
| SCHEMBL6018274 | 0.82 | PRSS1 (0.57) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10423618 | 0.82 | PRSS1 (0.57) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL16093023 | 0.81 | L3MBTL1 (0.67) | L3MBTL1MLYCDNAAACA2PLK1 | |
| SCHEMBL11062946 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MLYCDNAAACA2PLK1 | |
| SCHEMBL13494653 | 0.81 | L3MBTL1 (0.61) | L3MBTL1MLYCDNAAACA2HDAC1 | |
| SCHEMBL10356667 | 0.81 | PRSS1 (0.56) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11066925 | 0.80 | CA2 (0.58) | L3MBTL1MLYCDNAAACA2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |