SCHEMBL11065565

SCHEMBL11065565

Cc1c(COC2CCCCO2)cccc1-c1cnccn1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
KDM4C Q9H3R0 1/20 0.38
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CD274 Q9NZQ7 7/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
GABRA1 P14867 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRA5 P31644 1/20 0.35
GABRA3 P34903 1/20 0.35
GABRA2 P47869 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
DHFR P00374 1/20 0.34
P2RX7 Q99572 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11065601 0.85 ALDH1A1 (0.43) ALDH1A1HPGDKDM4CCD274ADRA1A
SCHEMBL8759380 0.81 KDM4C (0.35) KDM4CNPC1RAB9ACD274L3MBTL1
SCHEMBL11068192 0.74 KDM4C (0.38) ALDH1A1KDM4CNPC1RAB9AL3MBTL1
SCHEMBL8760072 0.74 KDM4C (0.38) KDM4CNPC1RAB9AL3MBTL1DHFR
SCHEMBL9453358 0.74 KDM4C (0.38) KDM4CNPC1RAB9ACD274L3MBTL1
SCHEMBL9442675 0.73 HTR6 (0.40) KDM4CNPC1RAB9AL3MBTL1DHFR
SCHEMBL18355699 0.72 TACR1 (0.46) KDM4CNPC1RAB9AMEN1KMT2A
SCHEMBL8760058 0.71 KDM4C (0.36) KDM4CNPC1RAB9AL3MBTL1DHFR
SCHEMBL8759396 0.71 MEN1 (0.36) ALDH1A1KDM4CNPC1RAB9AL3MBTL1
SCHEMBL9442671 0.71 KDM4C (0.36) KDM4CNPC1RAB9AL3MBTL1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4426524-A Heterocyclic substituted benzyl alcohol, insecticidal ester derivatives, and intermediates FMC CORPORATION (US) 1984-01-17 US disclosed