Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL11065656

CCOC(=O)C(C)C(=O)OC.N

nearest known ligand 0.46

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 1/20 0.46
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
ALOX15 P16050 1/20 0.40
SOAT1 P35610 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA14 Q9ULX7 2/20 0.38
CAD P27708 1/20 0.37
MMP8 P22894 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TRPA1 O75762 1/20 0.37
TSHR P16473 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4658427 1.00 MGAM (0.46) MGAMGAASIMGAM2ALDH1A1
Ammonia Solution, Strong SCHEMBL28791130 0.92 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL141446 0.89 ALDH1A1 (0.53) MGAMGAASIMGAM2ALDH1A1
SCHEMBL28186389 0.87 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8800602 0.87 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
Ethane SCHEMBL9181718 0.87 ALDH1A1 (0.50) MGAMGAASIMGAM2ALDH1A1
SCHEMBL275280 0.84 SMN1; SMN2 (0.52) ALDH1A1SMN1; SMN2CA1CA2CA14
SCHEMBL27437489 0.81 CA1 (0.41) ALDH1A1HPGDLMNAHSD17B10SMN1; SMN2
SCHEMBL10805452 0.81 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2CA1CA2CA14
SCHEMBL26658220 0.81 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2CA1CA2CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447431-A VIRICIDES, ANTIINFLAMMATORY AND SUNCREEN AGENT CIBA-GEIGY CORPORATION (US) 1984-05-08 US disclosed