Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753265 | 0.79 | PGR (0.48) | KDM4EKMT2AHSD11B1HTTSMN1; SMN2 | |
| SCHEMBL198220 | 0.74 | KDM4E (0.57) | ALDH1A1L3MBTL1KDM4EHSD11B1HTT | |
| SCHEMBL198040 | 0.72 | SMN1; SMN2 (0.65) | ALDH1A1L3MBTL1KDM4EKMT2AHTT | |
| SCHEMBL29384019 | 0.70 | MCL1 (0.53) | ALDH1A1L3MBTL1KDM4EHPGDTSHR | |
| SCHEMBL198460 | 0.70 | MCL1 (0.53) | ALDH1A1L3MBTL1KDM4EHPGDTSHR | |
| SCHEMBL4589791 | 0.70 | MCL1 (0.56) | ALDH1A1L3MBTL1KDM4EHTTMAPT | |
| SCHEMBL31239603 | 0.70 | MCL1 (0.56) | ALDH1A1L3MBTL1KDM4EHTTMAPT | |
| SCHEMBL11596069 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1L3MBTL1KMT2APOLBTSHR | |
| SCHEMBL11873902 | 0.70 | KDM4E (0.52) | ALDH1A1L3MBTL1KDM4EKMT2AHSD11B1 | |
| SCHEMBL5068459 | 0.69 | MCL1 (0.57) | ALDH1A1L3MBTL1KDM4EHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001514-B1 | HERBICIDAL SULFONAMIDES, AND PREPARATION AND USE THEREOF | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |
| US-4443244-A | TRIAZINES AND PYRIMIDINES, PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
| US-4339266-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4257802-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0001514-A2 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |