SCHEMBL5068459

SCHEMBL5068459

O=S(=O)(c1cc(Cl)ccc1Cl)c1cc(Cl)ccc1Cl

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.57
ALDH1A1 P00352 3/20 0.57
AKR1B1 P15121 1/20 0.56
TSHR P16473 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
USP2 O75604 1/20 0.52
GAA P10253 1/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.49
TP53 P04637 2/20 0.48
ACHE P22303 1/20 0.47
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
MAPK1 P28482 1/20 0.46
PKM P14618 1/20 0.46
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9475478 0.87 ALDH1A1 (0.60) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL29384019 0.86 MCL1 (0.53) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL198460 0.86 MCL1 (0.53) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL3009009 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL78760 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL5078515 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL78762 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
Hydrochloric Acid SCHEMBL8922332 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
SCHEMBL3695138 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1
Hydrochloric Acid SCHEMBL11157085 0.84 ALDH1A1 (0.52) MCL1ALDH1A1AKR1B1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100558793-C Ion conductive random copolymers POLYFUEL INC (US) 2009-11-11 CN disclosed
US-7354679-B2 Ion conductive random copolymers POLYFUEL, INC. (US) 2008-04-08 US disclosed
EP-1704174-A4 ION CONDUCTIVE RANDOM COPOLYMERS POLYFUEL INC (US) 2007-05-30 EP disclosed
CN-1902261-A Ion conductive random copolymers POLYFUEL INC (US) 2007-01-24 CN disclosed
EP-1704174-A2 ION CONDUCTIVE RANDOM COPOLYMERS Polyfuel, Inc. (US) 2006-09-27 EP disclosed
US-20050181256-A1 Sulfonated PEEK; polythioethers, polysulfones; copolymers; polymer electrolyte membranes used in fuel cells; proton conductivity, methanol-resistance, chemical stability and methanol crossover UNIVERSITY OF NORTH FLORIDA BOARD OF TRUSTEES 2005-08-18 US disclosed
WO-2005050671-A2 ION CONDUCTIVE RANDOM COPOLYMERS POLYFUEL, INC. (US) 2005-06-02 WO disclosed