Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH4 | P08319 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11456185 | 0.83 | EPHX1 (0.41) | HTTEPHX1MEN1KMT2AADH1B | |
| SCHEMBL15160469 | 0.80 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL104714 | 0.80 | ADH1B (0.44) | HTTEPHX1ADH1BADH1CADH1A | |
| SCHEMBL22899465 | 0.80 | ADH1B (0.44) | HTTEPHX1ADH1BADH1CADH1A | |
| SCHEMBL14176594 | 0.80 | ADH1B (0.44) | HTTEPHX1ADH1BADH1CADH1A | |
| SCHEMBL12404701 | 0.79 | HTT (0.39) | HTTEPHX1MEN1KMT2AADH1B | |
| SCHEMBL105260 | 0.77 | HTT (0.41) | HTTEPHX1ADH1BADH1CADH1A | |
| SCHEMBL22736288 | 0.77 | HTT (0.36) | HTTEPHX1MEN1KMT2AADH1B | |
| SCHEMBL20999947 | 0.76 | CYP2D6 (0.41) | EPHX1MEN1KMT2AADH1BADH1C | |
| SCHEMBL30775627 | 0.76 | CYP2D6 (0.41) | EPHX1MEN1KMT2AADH1BADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |