Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27278853 | 1.00 | EHMT2 (0.49) | EHMT2CYP2C19HPGDCYP3A4GAA | |
| SCHEMBL10982420 | 0.86 | EHMT2 (0.46) | EHMT2CYP2C19HPGDCYP3A4GAA | |
| SCHEMBL7275104 | 0.85 | HCRTR1 (0.47) | EHMT2CYP2C19CYP3A4TSHR | |
| SCHEMBL7275111 | 0.85 | HCRTR1 (0.47) | EHMT2CYP2C19CYP3A4TSHR | |
| SCHEMBL30829326 | 0.85 | HCRTR1 (0.47) | EHMT2CYP2C19CYP3A4TSHR | |
| SCHEMBL22443602 | 0.82 | HCRTR1 (0.52) | EHMT2CYP2C19CYP3A4ALDH1A1TSHR | |
| SCHEMBL22443601 | 0.82 | HCRTR1 (0.52) | EHMT2CYP2C19CYP3A4ALDH1A1TSHR | |
| SCHEMBL21538635 | 0.82 | ALDH1A1 (0.50) | EHMT2CYP2C19HPGDCYP3A4GAA | |
| SCHEMBL10215486 | 0.81 | P2RX7 (0.47) | EHMT2CYP2C19HPGDCYP3A4GAA | |
| SCHEMBL1914402 | 0.81 | GSK3A (0.43) | EHMT2CYP2C19HPGDCYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | claimed |
| US-4435322-A | Heterocyclic compounds containing an alkoxycarbonyl and a substituted methyl group | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-03-06 | — | — | US | disclosed |