Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.58 |
| ▸ | LTA4H | P09960 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30586506 | 1.00 | ACE (0.58) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL30586508 | 0.93 | ACE (0.57) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL30407371 | 0.91 | ACE (0.55) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL7259788 | 0.90 | ACE (0.64) | ACEACE2LTA4H | |
| SCHEMBL7259790 | 0.90 | ACE (0.64) | ACEACE2LTA4H | |
| SCHEMBL30407343 | 0.89 | OPRD1 (0.55) | ACEACE2OPRM1OPRD1 | |
| SCHEMBL5030487 | 0.89 | ACE (0.54) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL5030497 | 0.89 | ACE (0.54) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL29666775 | 0.88 | ACE (0.54) | ACEACE2LTA4HOPRM1OPRD1 | |
| SCHEMBL5026882 | 0.87 | ACE (0.54) | ACEACE2LTA4HOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465625-A | ANALGESICS | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1984-08-14 | — | — | US | disclosed |