SCHEMBL7259790

SCHEMBL7259790

C[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACE P12821 16/20 0.64
ACE2 Q9BYF1 8/20 0.64
LTA4H P09960 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7259788 1.00 ACE (0.64) ACEACE2LTA4H
SCHEMBL29666707 0.96 ACE (0.60) ACEACE2LTA4H
SCHEMBL30010736 0.92 ACE (0.56) ACEACE2
SCHEMBL30051261 0.92 ACE (0.62) ACEACE2LTA4H
SCHEMBL28255253 0.90 ACE (0.63) ACEACE2LTA4H
SCHEMBL28255251 0.90 ACE (0.63) ACEACE2LTA4H
SCHEMBL30586506 0.90 ACE (0.58) ACEACE2LTA4H
SCHEMBL11065987 0.90 ACE (0.58) ACEACE2LTA4H
SCHEMBL30051643 0.90 ACE (0.60) ACEACE2
SCHEMBL30440345 0.90 ACE (0.60) ACEACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
US-12227736-B2 Stenotrophomonas maltophilia GYH and application thereof in degradation of chlorinated hydrocarbon pollutants ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-02-18 US disclosed
EP-3800243-B1 BACTERIUM DEGRADING LAS AND N AND USE THEREOF AGRO ENVIRONMENTAL PROT INSTITUTE MINISTRY OF AGRICULTURE AND RURAL AFFAIRS (CN) 2023-09-27 EP disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
US-20220275324-A1 STENOTROPHOMONAS MALTOPHILIA GYH AND APPLICATION THEREOF IN DEGRADATION OF CHLORINATED HYDROCARBON POLLUTANTS ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2022-09-01 US disclosed
US-6649365-B1 Tracer agent, of given formula, comprising acyl residue of an amino acid or a peptide; fluorescence; colorimetric analysis; use in identifying microorganisms BIO MERIEUX (FR) 2003-11-18 US disclosed
EP-1051509-A1 USE OF INDOLAMINE DERIVATIVES FOR DETECTING MICRO-ORGANISM PEPTIDASE BIO MERIEUX (FR) 2000-11-15 EP disclosed
WO-1999038995-A1 USE OF INDOLAMINE DERIVATIVES FOR DETECTING MICRO-ORGANISM PEPTIDASE BIO MERIEUX (FR) 1999-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP ACE 1190/4885ACE2 1622/4885LTA4H 3533/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD ACE 486/4885ACE2 675/4885LTA4H 1299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.