Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 14/20 | 0.66 |
| ▸ | MAOA | P21397 | 13/20 | 0.66 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289343 | 0.99 | MAOB (0.65) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL10900191 | 0.96 | MAOB (0.67) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL11287532 | 0.92 | MAOB (0.67) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL16059342 | 0.86 | MAOB (0.67) | MAOBMAOADRD2 | |
| SCHEMBL16409766 | 0.85 | HDAC1 (0.68) | MAOBMAOAPDE3BPDE3A | |
| SCHEMBL10898729 | 0.85 | MAOB (0.67) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL14815990 | 0.84 | MAOA (0.65) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL6585538 | 0.84 | MAOB (0.68) | MAOBMAOAPDE3BPDE3ADRD2 | |
| SCHEMBL8212260 | 0.84 | MAOB (0.72) | MAOBMAOADRD2 | |
| SCHEMBL11603568 | 0.83 | PDE3B (0.57) | MAOBMAOAPDE3BPDE3ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |