Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.63 |
| ▸ | BID | P55957 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL301121 | 0.90 | HMGB1 (0.67) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL20162476 | 0.86 | FOLH1 (0.61) | BIDBCL2L1MCL1BAK1SMN1; SMN2 | |
| SCHEMBL20696108 | 0.84 | BID (0.54) | BIDBCL2L1MCL1BAK1SMN1; SMN2 | |
| SCHEMBL18038407 | 0.83 | BID (0.65) | BIDBCL2L1MCL1BAK1SMN1; SMN2 | |
| SCHEMBL8677351 | 0.83 | PTGER1 (0.64) | HMGB1MCL1ALDH1A1PTGER1PTGER4 | |
| SCHEMBL11710027 | 0.82 | FOLH1 (0.61) | BIDBCL2L1MCL1BAK1SMN1; SMN2 | |
| SCHEMBL9304814 | 0.82 | FFAR1 (0.52) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL28400709 | 0.81 | HMGB1 (0.65) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL39812 | 0.81 | HMGB1 (0.65) | HMGB1BIDBCL2L1MCL1BAK1 | |
| SCHEMBL112902 | 0.81 | PTPN1 (0.65) | HMGB1SMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4455298-A | MOLLUSC EXTRACT | MCFARLANE STUART J (NZ) | 1984-06-19 | — | — | US | disclosed |
| EP-0010061-B1 | PHARMACEUTICAL PREPARATIONS CONTAINING A MOLLUSC EXTRACT | Mc Farlane, Stuart John (NZ) | 1983-07-13 | — | — | EP | disclosed |
| WO-1980000661-A1 | PHARMACEUTICAL PREPARATIONS | CROFT J (NZ) | 1980-04-17 | — | — | WO | disclosed |
| EP-0010061-A1 | Pharmaceutical preparations containing a mollusc extract | Mc Farlane, Stuart John (NZ) | 1980-04-16 | — | — | EP | disclosed |